Asthme

2024


Nadia Suray Tan

McMaster University
Bourse d’études, $10,500

Role of B cells in mediating inflammation, autoimmunity and clinical symptoms in respiratory diseases

En partenariat avec la Fondation canadienne d’allergie, d’asthme et d’immunologie (CAAIF) et le Réseau canadien de recherche respiratoire (RCRR).

2023


Francis Lissanga Dendo

Université de Moncton
Bourse de voyage, RCRR AGA, $1500

Asthme et pollution atmosphérique au Nouveau Brunswick

Clarus Leung

University of British Columbia
Fellowship clinique, $33,000

Endo-phenotyping of asthma and COPD overlap by airway inflammation

Approximately one-third of asthma and COPD patients have features of asthma- COPD overlap or ACO. These patients experience worse symptoms and more serious respiratory attacks than those with asthma or COPD alone. ACO is under-recognized, under-diagnosed and may be improperly treated because of the limited understanding of its biology. Dr. Clarus Leung’s post-doctoral research at UBC will help uncover the disease mechanisms of ACO so that clinicians can better diagnose and prescribe the most effective therapies for ACO.

Dr. Leung will investigate the underlying inflammatory mechanisms in the airways of patients with ACO, collecting tissue samples and cells from the airways of volunteers with ACO using a technique called bronchoscopy to identify the key airway inflammation features of ACO. Dr. Leung will use high-resolution imaging techniques to investigate how inflammation relates to persistent changes in the structure of the airways and the lungs.


Shirley Quach & Teresa To

Hospital for Sick Children
Bourse d’études du programme de recherche paramédicale, $10,000

Does the use of biologics in children with severe asthma improve health outcomes and quality of life? – A longitudinal cohort study

 

2022


Cristina Longo, Université de Montréal
Prix du chercheur(se) en début de carrière en asthme*$100,000

Treating asthma by integrating learning algorithms with omics research: Moving toward automated high-dimensional endotyping in children (TAILOR-MADE)

Zihang Lu, Queen’s University
Prix du chercheur(se) en début de carrière en asthme*, $100,000

Asthma phenotypes, risk factors and the implications for future management in Canadian children

Maria Medeleanu, SickKids
Bourse d’études, $21,000

Interrogating the link between early viral infections and childhood asthma

Dheerendra Pandey, University of Manitoba
Bourse d’études, $14,000

Multidimensional role of CD38 in oxidized phosphatidylcholine (OxPCs) induce obstructive lung diseases

 

2020


Jigneshkumar Vaghasiya, University of Manitoba
Bourse d’études, $10,500

Oxidized phosphatidylcholines are unique drivers of asthma pathobiology

 

2018 


Kozeta Miliku, University of Manitoba
Fellowship, $90,000

The role of human milk oligosaccharides in the developmental origins of lung function and asthma

 

*Led by Asthma Canada in partnership with AstraZeneca Canada, Canadian Allergy, Asthma and Immunology Foundation (CAAIF) and the Canadian Institutes of Health Research’s Institute of Circulatory and Respiratory Health (CIHR-ICRH) 

Santé pulmonaire des enfants

2020


Chelsea Morin, University of Alberta
Fellowship, $55,000

A randomized control trial comparing three methods of cardiopulmonary resuscitation using an infant piglet model of asphyxia

Tara Janes, University of Alberta
Fellowship, $45,000

Progesterone promotes respiratory recovery in a rat model of congenital central hypoventilation syndrome: site of action and mechanisms

Shirley Quach, University of Ontario Institute of Technology Paramédicale
Fellowship, $10,000)

The pediatric mechanical ventilation in Canada (PeMViC) study: A Delphi survey of pediatric mechanical ventilation practices by Canadian respiratory therapists

 

2019 


Kawsari Abdullah, Children’s Hospital of Eastern Ontario Research Institute
Fellowship, $54,000

Long-term respiratory outcome of children diagnosed with bronchiolitis in the first year of life: A prospective cohort study using linked clinical and health administrative data

Chanèle Cyr-Depauw, Ottawa Hospital Research Institute
Bourse d’études, $12,000

Defining the next-generation umbilical cord-derived cell-therapy for treatment of neonatal lung disease

Shirley Quach, University of Ontario Institute of Technology Paramédicale
Fellowship, $10,000

Common Canadian practices of pediatric mechanical ventilation

Toux chronique

2022


Nermin Diab, McMaster University
Fellowship, $55,000

Mepolizumab for the Treatment of Chronic Cough with Eosinophilic Airways Disease

La maladie pulmonaire obstructive chronique (MPOC)

2025

Reginald Smyth, Queen’s University 
Ph. D. bourse d’études

A novel clinical physiology platform to investigate the effects of inhaled bronchodilator therapies on small airway function, operating lung volumes, and neuromechanical dissociation (SOUND): Consequences for exertional dyspnea in hyperinflated patients with COPD​

This study will explore if improving the function of small air tubes in the lungs, patients with COPD will have less air trapped, reducing signals to the diaphragm and lessening shortness of breath. 
 

2024


Jeenat Mehareen, University of British Columbia
Bourse d’études

Economic evaluation of integrating a precision medicine tool for predicting exacerbations into routine clinical care of chronic obstructive pulmonary disease

En partenariat avec le Réseau canadien de recherche respiratoire (RCRR)

Gaurav Veer Singh, Toronto Metropolitan University
Bourse d’études

Fractal analysis of pulmonary vasculature in chronic obstructive pulmonary disease: Association with pulmonary function, functional capacity and symptoms

2023


Konstiantyn Dmytriiev, University of Alberta
Bourse d’études, $10,500

Pulmonary vascular dysfunction and exercise in chronic obstructive pulmonary disease

Tania Janaudis-Ferreira, McGill University
Bourse d’études du programme de recherche paramédicale, $10,000

Remote Physical Function Assessment in Chronic Obstructive Pulmonary Disease

Shirley Quach, McMaster University
Fellowship paramédicale, $5,000

Perceptions and Usability of Publicly Available Chronic Obstructive Pulmonary Disease Apps

2022


Carli Peters, University of British Columbia
Fellowship, $45,000

Utilizing optical coherence tomography and exercise to develop novel biomarkers of respiratory impairment in people living with human immunodeficiency virus

Mika Nonoyama, Ontario Technical University
Bourse d’études du programme de recherche paramédicale, $20,000

Testing the effects of temperature and humidity on individuals with COPD in the ACE climactic chamber: A feasibility and pilot study

Fatemeh Aminazadeh, University of British Columbia
Bourse d’études, $21,000

The contribution of sex differences to small airways disease in Chronic Obstructive Pulmonary Disease (COPD)

In Canada and other developed countries around the world, the number of hospitalizations and deaths due to COPD is now greater for females than males. Despite this, females are less likely to receive spirometry testing, specialty referrals, or a physician diagnosis of COPD compared to males. This project will help by generating new knowledge on sex differences in the development of COPD. These data will provide researchers with new targets for early treatment of COPD, and help clinicians better diagnose female COPD patients to improve disease outcomes.

Meghan Koo, Toronto Metropolitan University
Bourse d’études, $15,667

Inspiration-expiration CT texture-based delta radiomics: a new biomarker associated with COPD symptoms?

Dmitry Rozenberg, University Health Network
$500

Translating the Interplay of Cognition and Physical Performance to Daily Activities in COPD and ILD – Identifying Needs and Research Priorities

2021


Dina Brooks, University of British Columbia
Bourse d’études du programme de recherche paramédicale, $20,000

A mobile electronic repository to address patients’ support needs in coping with chronic obstructive pulmonary disease

Shirley Quach, University of British Columbia
Fellowship paramédicale, $10,000

A mobile electronic repository to address patients’ support needs in coping with chronic obstructive pulmonary disease

2020


Tania Janaudis-Ferreira, Research Institute of the McGill University Health Centre
Bourse d’études du programme de recherche paramédicale, $35,000

Improving ACCEPTance and uptake of pulmonary rehabilitation after acute exacerbation of chronic obstructive pulmonary disease: The ACCEPT PR STUDY

2019


Sunita Mulpuru, Ottawa Hospital Research Institute Emerging Clinician Scientist Award, $175,000

Avec nos partenaires IRSC-ISCR et Astra Zeneca Canada

Validating the use of frailty measurements to predict care expectations and deteriorations in quality of life among people with COPD: A prospective cohort study

 

2018


Dina Brooks, West Park Healthcare Centre
Bourse d’études du programme de recherche paramédicale, $20,000

Perspectives of Patients with COPD and Healthcare Providers on an Intervention to Reduce Sedentary Behaviour

Devin Phillips, University of Alberta
Bourse d’études, $10,500

The effect of inhaled nitric oxide on dyspnea and exercise tolerance in mild chronic obstructive pulmonary disease

Sachi O’Hoski, McMaster University
Fellowship paramédicale $10,000

Beyond function: Exploring participation in life roles in people with COPD

Nafeez Syed, University of British Columbia
Fellowship paramédicale, $10,000

Impact of diesel exhaust on exercise endurance, breathlessness and airway physiology in mild-to-moderate chronic obstructive pulmonary disease

2017


Kate Johnson, University of British Columbia
Bourse d’études, $42,000

Evaluating strategies for early detection of chronic obstructive pulmonary disease

Didier Saey, Université Laval
Bourse d’études du programme de recherche paramédicale, $20,000

Measuring quadriceps muscle endurance in patients with COPD

Subventions catalyseurs en MPOC

Each Catalyst Grant is worth $30,000

2025

Graeme Koelwyn, Simon Fraser University 

Inflammatory memory in chronic obstructive pulmonary disease  


Devin Phillips, York University

The impact of pulmonary vascular dysfunction on breathlessness in COPD    
     


2020 

Avec nos partenaires IRSC-ISCR

Sunita Mulpuru, Ottawa Hospital Research institute 

A pilot feasibility study to inform the development of a novel clinical and biomarker-driven definition of COPD exacerbation among hospitalized adults in Canada


Christel Renoux, CIUSSS de Centre-Ouest-de-l’Ile-de-Montréal-Jewish General 

Gabapentinoids and the risk of severe respiratory events in patients with chronic obstructive pulmonary disease


Dimitry Rozenberg, University Health Network 

Feasibility of a Home-Based Cognitive-Physical Exercise Program in Chronic Obstructive Pulmonary Disease Patients: A Pilot Randomized Control Trial


Benjamin Smith, Research Institute of the McGill University Health Centre 

Airway trees in the Anthropocene: A new paradigm for personalizing COPD prevention, prognosis, and pharmacotherapy


2019 

Avec nos partenaires IRSC-ISCR

Pat Camp, University of British Columbia 

COPD Alert! Telehealth System


Christopher Carlsten, University of British Columbia 

Effect of diesel exhaust exposures on the lung microbiome in COPD


Roger Goldstein, University of Toronto 

Rapid access rehabilitation (RAR) post-hospitalization for acute exacerbations of chronic obstructive pulmonary disease: A feasibility study


2018 

Laurent Brochard, St. Michael’s Hospital 

High-flow nasal cannula versus non-invasive ventilation in exacerbations of chronic obstructive pulmonary disease


Thomas Rotter, Queen’s University 

Optimizing integrated care for older adults with COPD: Determining the influence of the primary and specialist network of care on patient and system outcomes


Robert Wu, University Health Network 

Identification of patients admitted with COPD exacerbations and stratification of those at high risk of readmission using natural language processing and machine learning


2017 COPD 

Andrew Cave, University of Alberta

Natural history of COPD in primary care: A national retrospective cohort study


Dennis Jensen, McGill University

Morphine: A novel intervention to maximize the benefits of exercise training in adults with COPD?


Ma’en Obeidat, University of British Columbia

The effect of sex on molecular signatures in lung tissue from COPD patients

Soins cliniques

2025

Christopher Farley, McMaster University
Fellowship paramédicale

The effects of post-hospital rehabilitation on physical function in survivors of critical illness: A systematic review and meta-analysis​

Using a breathing machine in the ICU can cause weakness when it comes to muscles that help you breathe, leading to loss of activity and productivity after discharge. This project will help develop a post-discharge exercise program to help patients return to work and activities.

Annia Schreiber, University of Toronto 
Post-doctoral/Clinical Fellowship

Muscle recruitment during neck flexion and inspiratory muscle training in difficult and prolonged weaning patients: a physiological study: The FLEX study​

This study will test the feasibility, safety, benefits, timing and tolerance of a new rehabilitation approach for patients using mechanical ventilation.

Catriona Steele, University Health Network (Toronto) 
Bourse d’études du programme de recherche paramédicale

Canadian Survey on Dysphagia in Chronic Respiratory Diseases​

This survey will look at how common swallowing problems are and how they affect breathing for those with breathing disorders, with the goal of creating advocacy and education resources to support this population.

Ben Thompson, University of Calgary 
Ph. D. bourse d’études

Investigating sex-based differences in the diaphragm blood response following inspiratory muscle training​

Evidence suggests females respond differently to inspiratory muscle training​ (IMT) than males. This study will compare the differences in blood flow to the diaphragm as a result of IMT. 

2024


Christopher Farley, McMaster University
Fellowship paramédicale

The needs and preferences of critical illness survivors for post-ICU rehabilitation: A mixed methods study

Luca Salvatore Menga, University of Toronto
Bourse d’études

Mechanical ventilation targeting individualized lung recruitment and minimal lung distention with electrical impedance tomography and diagnostic oscillometry in ARDS: The MAC-TEN study

Shirley Quach, SickKids
Fellowship

Effectiveness, safety, and equity of virtual care for people with respiratory diseases beyond the pandemic

Annia Schreiber, University of Toronto
Fellowship

Physiological evaluation of accessory muscle activity and function after traumatic spinal cord injury – the ACCESSIT study  

 

2017


Louise Rose, University of Toronto
Bourse d’études du programme de recherche paramédicale

Patient and family centered performance measures focused on actionable processes of care for persistent or chronic critical illness

Erin Miller, University of Toronto
Fellowship paramédicale

Evaluating the effectiveness of using high fidelity stimulation to teach tracheal suctioning to physical therapists

COVID-19 et le syndrome post-COVID-19

2021 Respiratory Health Effects of Long COVID Operating Grants

Avec nos partenaires IRSC-ISCR/ISG


Jordan Guenette, University of British Columbia ($40,000)

Cardiopulmonary exercise testing and functional imaging determinants of dyspnea post-COVID-19


Robert Kozak, Sunnybrook Health Sciences Centre ($40,000)

Host gene expression signatures from clinically banked upper respiratory tract swabs associate in situ altered mucosal immunity with development of long COVID-19


Simon Rousseau, Research Institute of the McGill University Health Centre ($40,000)

Immunopathology of respiratory distress in long COVID


Alyson Wong, University of British Columbia ($40,000)

Identifying long COVID phenotypes and their association with long-term quality of life

Fibrose kystique

2023


Razieh Enjilela, Toronto Metropolitan University
Fellowship, $27,000

Development of Magnetic Resonance Imaging Airway Segmentation to Assess and Monitor Cystic Fibrosis Lung Disease

 

2022


Jordana McMurray, University of Toronto
Fellowship paramédicale, $10,000

Actigraphic and self-reported sleep outcomes and relationships to anxiety and depression symptoms in adolescents and young adults with cystic fibrosis: A mixed-methods study

in partnership with Cystic Fibrosis Canada

Andrea Murru, CHU de Québec-Université Laval
Bourse d’études, $21,000

Functional Characterization of Low-Density Neutrophils in Cystic Fibrosis: Clinical Implications

Yuetong Song, University of Toronto
Bourse d’études, $21,000

Modeling Human iPSC-derived Alveolar Type 1 and 2 Cells for Cystic Fibrosis Lung Disease

2018


Adèle Coriati, Providence St. Joseph’s and St. Michael’s Healthcare
Fellowship, $90,000

Understanding differences in cystic fibrosis health outcomes and survival: A systematic comparison of Canadian and French registry data

Kenneth Wu, University of Toronto
Fellowship paramédicale, $10,000

Characteristics of peripheral skeletal muscles structure and function in adults with cystic fibrosis (CF) & its relationship with CF transmembrane conductance regulator (CFTR) malfunction

 

2017


Sunita Mathur, University of Toronto
Bourse d’études du programme de recherche paramédicale, $20,000

Determinants of skeletal muscle function in adults with cystic fibrosis

Maladies infectieuses et immunologie

2022

Danuzia Marques, Université Laval
Fellowship, $30,000

Linking neonatal stress and anomalies of immune development in rats: novel insights into the origin of sex-based differences in viral infection severity

Nicole Sarden, University of Calgary
Bourse d’études, $13,500

Investigating the role of neutrophils during respiratory viral infections

2018


Craig Dale, University of Toronto
Bourse d’études du programme de recherche paramédicale, $20,000

A multi-centered stepped wedge cluster randomized controlled trial (RCT) of the de-adoption of oral chlorhexidine prophylaxis and implementation of an oral care bundle for ventilated critically ill patients (The CHORAL study)

Cameron Griffiths, University of Alberta
Bourse d’études, $10,500

Interactions between respiratory syncytial virus and cell surface nucleolin during viral entry

Maladie pulmonaire interstitielle (MPI)

2021


Gillian Goobie, University of British Columbia
Fellowship, $55,000

Air pollution as a modulator of molecular, structural, and clinical outcomes in patients with fibrotic interstitial lung disease

 

2019


Joyce Ka Yan Wu, Toronto General Hospital
Bourse d’études du programme de recherche paramédicale, $20,000

Characterization of interstitial lung disease using airway oscillometry

Le cancer du poumon

2023


Hadrien Gayap Tagheu, Université de Moncton
Bourse de voyage, RCRR AGA, $1500

Deep Machine Learning for Medical Diagnosis, Application to Lung Cancer Detection

En partenariat avec Recherche Nouveau-Brunswick

2018


Javad Alizadeh, University of Manitoba
Bourse d’études, $42,000

Stiff substrates enhance mitophagy/EMT crosstalk

Greffe pulmonaire

2025


Joyce Wu, University Health Network (Toronto) 
Bourse d’études du programme de recherche paramédicale

Feasibility of lung function home monitoring using respiratory oscillometry after lung transplant​

This study explores whether home monitoring with handheld, standalone oscillometry devices help to detect acute rejection post lung transplant earlier than in-hospital spirometry.

2022


Anne Fu, University of Toronto
Bourse d’études

Respiratory Oscillometry for Early Diagnosis of Chronic Rejection After Lung Transplant

Santé publique / Santé de la population

2025

Sophie Collins, McGill University 
Post-doctoral/Clinical Fellowship

Association of a novel index of early life growth adversity with later-life lung structure and function ​

Early life growth conditions may be important risk factors for later lung disease. This study explores whether height-GaP is associated with lung function later in life.

2023


Cole Bowerman, Dalhousie University
Bourse d’études

Hidden Amongst Healthy: Normalization of Respiratory Pathology and Health Disparities by Reference Equations

Fibrose pulmonaire

2024


Samin Abbasidezfouli, University of British Columbia
Bourse d’études, $8,500

Cartilage-associated protein (CRTAP) as an environmentally sensitive target in idiopathic pulmonary fibrosis 

2022


Olivia Ferguson, University of British Columbia
Bourse d’études, $10,667

The physiological mechanisms of improved exertional dyspnoea and functional exercise capacity associated with antifibrotic therapy in patients with idiopathic pulmonary fibrosis (IPF)

2021


Carlos Hiroki, University of Calgary
Bourse d’études, $10,500

Lung sensory neurons influence in the outcome of pulmonary fibrosis

CIHR Project Grant

2017


Miranda Kirby, University of British Columbia
Fellowship, $45,000

Small airway disease and emphysema in idiopathic pulmonary fibrosis

Hypertension pulmonaire

2023


Saeid Maghsoudi, University of Manitoba
Bourse d’études

Inhibition of Adenylyl Cyclase Isoform 6 by Cysteine Nitrosylation in Hypoxic Pulmonary Hypertension, and Rescue with Novel Forskolin Derivatives

En partenariat avec l’Association pulmonaire du Manitoba

 

2019


Neil Goldenberg, Hospital for Sick Children
Emerging Clinician Scientist Award, $200,000

Immunological Dysfunction in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension

Avec nos partenaires IRSC-ISCR et Astra-Zeneca Canada

2017


Steven Wright, University of Toronto
Bourse d’études, $42,000

Exercise Hemodynamics for the Evaluation of Breathlessness & Suspected Pulmonary Arterial Hypertension

Sommeil et exercice

2025


Kristin MacLeod, Queen’s University
Fellowship paramédicale

The Effect of Continuous Positive Airway Pressure (CPAP) therapy on Daily Movement Behaviours and Exercise Capacity in Obstructive Sleep Apnea (OSA)

This study looks at how daytime sleepiness and fatigue affect the amount of physical activity undertaken by individuals with sleep apnea, and if treating sleep apnea leads to greater activity levels.

 2023


Felix Girard, McGill University
PhD Bourse d’études, $10,000

Effects of (Un)Loading Stimuli on the Human Diaphragm Activation at Rest and During Exercise: Implications for a Better Understanding of Dyspnea

2022


Silvia Cardani, University of Alberta
Fellowship, $45,000

Sex hormones and their use in hypoventilation syndromes: site of action and mechanism

Mohammadreza Hajipour, University of British Columbia
Bourse d’études, $21,000

Alternative metrics of sleep apnea severity derived from polysomnography

The apnea-hypopnea index (AHI) has served as a primary metric for assessing obstructive sleep apnea (OSA). Nevertheless, the literature reveals inconsistent findings regarding the correlation between AHI and adverse health outcomes. In our study, we present compelling evidence that a novel measure, event-related hypoxic burden, not only gauges the severity of respiratory events but also correlates with physiological responses to these events, distinguishing it from AHI. Consequently, these innovative metrics hold promise not only for predicting health outcomes but also for more precisely identifying patients who would benefit from treatment.

2018


Veronique Pepin, Concordia University
Bourse d’études du programme de recherche paramédicale, $20,000

APNex: A pilot randomized trial of combined cognitive-behavioural therapy and exercise training versus exercise training alone for the treatment of chronic insomnia in obstructive sleep apnea

Annette Pisanski (Abad-Hernandez), University of Alberta
Bourse d’études, $14,000

Role of parafacial respiratory group on the stabilization of sleep disordered breathing

Tabagisme et vapotage

2025


Makenna Gomes, University of Waterloo
Ph. D. bourse d’études​

Assessing the Health Risks of E-Cigarette Use Among Young People in Canada: A Longitudinal Study of Biomarkers of Exposure and Product Differences​

This study looks at biomarkers of exposure and potential harm in youth who vape compared to youth who smoke and youth who neither smoke nor vape to gain a better understanding of the harms of youth vaping.

2024


Cassie Gilchrist, University of British Columbia
Bourse d’études

Exploring the impact of cannabis smoke exposure on lung health with single-cell RNA sequencing and microbiome analysis

David Hammond, University of Waterloo
Subvention d’équipe des IRSC en santé pulmonaire

Youth behaviours, vaping and lung health

Devin Phillips, York University
Bourse d’études du programme de recherche paramédicale

Characterizing the physiological impact of electronic cigarette use in healthy young adults

 

2023


Maks Dziura, University of Windsor
Bourse d’études

Investigating the Isomeric Effect of Synthetic Nicotine on Respiratory Functionality

 

2022


Tina Afshar, University of British Columbia
Bourse d’études

Lung Health Effects of E-Cigarette Cessation

Feux de forêt et santé pulmonaire

2024

Paul Kubes, Queen’s University
Subvention d’équipe des IRSC en santé pulmonaire

Wildfire particles exacerbate asthma by increasing inflammation through neural and microbial alterations


2022

Justin Turner, University of British Columbia
Fellowship paramédicale

Thank you to our funding partners:

Wildfire Smoke and Emergency Planning for First Nations People Living with Lung Disease in Remote and Rural British Columbia